Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. - Télécom SudParis Access content directly
Journal Articles The Lancet Year : 2015

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition.

Christopher J L Murray , Ryan M Barber (1) , Kyle J Foreman , Ayse Abbasoglu Ozgoren , Semaw F Abera , Victor Aboyans (2, 3) , Jerry P Abraham , Ibrahim Abubakar , Laith J Abu-Raddad (4) , Niveen M Abu-Rmeileh , Tom Achoki , Ilana N Ackerman , Zanfina Ademi , Arsène K Adou , José C Adsuar , Ashkan Afshin , Emilie E Agardh , Sayed Saidul Alam , Deena Alasfoor , Mohammed I Albittar , Miguel A Alegretti , Zewdie A Alemu , Rafael Alfonso-Cristancho , Samia Alhabib , Raghib Ali , François Alla (5, 6) , Peter Allebeck (7) , Mohammad A Almazroa , Ubai Alsharif , Elena Alvarez (8) , Nelson Alvis-Guzman , Azmeraw T Amare , Emmanuel A Ameh , Heresh Amini (9) , Walid Ammar , H Ross Anderson (10) , Benjamin O Anderson (11) , Carl Abelardo T Antonio , Palwasha Anwari , Johan Arnlöv , Valentina S Arsic Arsenijevic , Al Artaman , Rana J Asghar , Reza Assadi (12) , Lydia S Atkins (13) , Marco A Avila , Baffour Awuah , Victoria F Bachman , Alaa Badawi , Maria C Bahit , Kalpana Balakrishnan (14) , Amitava Banerjee (15) , Suzanne L Barker-Collo , Simon Barquera , Lars Barregard , Lope H Barrero , Arindam Basu (16) , Sanjay Basu (17) , Mohammed O Basulaiman , Justin Beardsley , Neeraj Bedi , Ettore Beghi (18) , Tolesa Bekele , Michelle L Bell (19) , Corina Benjet , Derrick A Bennett (20) , Isabela M Bensenor , Habib Benzian , Eduardo Bernabé , Amelia Bertozzi-Villa , Tariku J Beyene , Neeraj Bhala , Ashish Bhalla , Zulfiqar A Bhutta , Kelly Bienhoff , Boris Bikbov , Stan Biryukov , Jed D Blore , Christopher D Blosser , Fiona M Blyth , Megan A Bohensky , Ian W Bolliger , Berrak Bora Başara , Natan M Bornstein (21) , Dipan Bose , Soufiane Boufous , Rupert R A Bourne , Lindsay N Boyers , Michael Brainin , Carol E Brayne (22) , Alexandra Brazinova , Nicholas J K Breitborde , Hermann Brenner , Adam D Briggs (23) , Peter M Brooks (24) , Jonathan C Brown , Traolach S Brugha , Rachelle Buchbinder , Geoffrey C Buckle , Christine M Budke (25) , Anne Bulchis , Andrew G Bulloch , Ismael R Campos-Nonato , Hélène Carabin , Jonathan R Carapetis , Rosario Cárdenas , David O Carpenter (26) , Valeria Caso , Carlos A Castañeda-Orjuela , Ruben E Castro (27) , Ferrán Catalá-López , Fiorella Cavalleri , Alanur Çavlin , Vineet K Chadha (28) , Jung-Chen Chang , Fiona J Charlson , Honglei Chen , Wanqing Chen (29) , Peggy P Chiang , Odgerel Chimed-Ochir , Rajiv Chowdhury (30) , Hanne Christensen (31) , Costas A Christophi (32, 33) , Massimo Cirillo , Matthew M Coates , Luc E Coffeng , Megan S Coggeshall , Valentina Colistro , Samantha M Colquhoun , Graham S Cooke (34) , Cyrus Cooper (35) , Leslie T Cooper , Luis M Coppola , Monica Cortinovis (36) , Michael H Criqui , John A Crump , Lucia Cuevas-Nasu , Hadi Danawi , Lalit Dandona , Rakhi Dandona , Emily Dansereau , Paul I Dargan , Gail Davey (37) , Adrian Davis , Dragos V Davitoiu , Anand Dayama , Diego de Leo , Louisa Degenhardt , Borja del Pozo-Cruz , Robert P Dellavalle , Kebede Deribe , Sarah Derrett , Don C Des Jarlais , Muluken Dessalegn , Samath D Dharmaratne , Mukesh K Dherani , Cesar Diaz-Torné , Daniel Dicker , Eric L Ding , Klara Dokova , E Ray Dorsey , Tim R Driscoll , Leilei Duan , Herbert C Duber , Beth E Ebel , Karen M Edmond , Yousef M Elshrek , Matthias Endres , Sergey P Ermakov , Holly E Erskine , Babak Eshrati , Alireza Esteghamati , Kara Estep , Emerito Jose A Faraon , Farshad Farzadfar , Derek F Fay , Valery L Feigin , David T Felson (38) , Seyed-Mohammad Fereshtehnejad , Jefferson G Fernandes (39) , Alize J Ferrari (40) , Christina Fitzmaurice , Abraham D Flaxman , Thomas D Fleming (41) , Nataliya Foigt , Mohammad H Forouzanfar , F Gerry R Fowkes , Urbano Fra Paleo , Richard C Franklin , Thomas Fürst , Belinda Gabbe , Lynne Gaffikin , Fortuné G Gankpé , Johanna M Geleijnse (42) , Bradford D Gessner , Peter Gething (43) , Katherine B Gibney , Maurice Giroud , Giorgia Giussani (18) , Hector Gomez Dantes , Philimon Gona , Diego González-Medina , Richard A Gosselin , Carolyn C Gotay , Atsushi Goto , Hebe N Gouda , Nicholas Graetz , Harish C Gugnani , Rahul Gupta (44) , Rajeev Gupta (44) , Reyna A Gutiérrez (45) , Juanita Haagsma , Nima Hafezi-Nejad , Holly Hagan , Yara A Halasa , Randah R Hamadeh , Hannah Hamavid , Mouhanad Hammami (46) , Jamie Hancock (47) , Graeme J Hankey , Gillian M Hansen (48) , Yuantao Hao , Hilda L Harb (49) , Josep Maria Haro , Rasmus Havmoeller , Simon I Hay , Roderick J Hay , Ileana B Heredia-Pi , Kyle R Heuton , Pouria Heydarpour (50) , Hideki Higashi , Martha Hijar , Hans W Hoek , Howard J Hoffman , H Dean Hosgood , Mazeda Hossain (51) , Peter J Hotez , Damian G Hoy (52) , Mohamed Hsairi , Guoqing Hu (53) , Cheng Huang (54) , John J Huang , Abdullatif Husseini , Chantal Huynh , Marissa L Iannarone , Kim M Iburg , Kaire Innos , Manami Inoue , Farhad Islami , Kathryn H Jacobsen , Deborah L Jarvis (55) , Simerjot K Jassal , Sun Ha Jee , Panniyammakal Jeemon , Paul N Jensen (56) , Vivekanand Jha , Guohong Jiang (57) , Ying Jiang (58) , Jost B Jonas (59) , Knud Juel , Haidong Kan , André Karch , Corine K Karema , Chante Karimkhani , Ganesan Karthikeyan , Nicholas J Kassebaum , Anil Kaul (60) , Norito Kawakami , Konstantin Kazanjan , Andrew H Kemp (61) , Andre P Kengne (62) , Andre Keren , Yousef S Khader , Shams Eldin A Khalifa (63) , Ejaz A Khan , Gulfaraz Khan , Young-Ho Khang , Christian Kieling , Daniel Kim , Sungroul Kim (64) , Yunjin Kim , Yohannes Kinfu , Jonas M Kinge , Miia Kivipelto (65) , Luke D Knibbs , Ann Kristin Knudsen (66) , Yoshihiro Kokubo , Soewarta Kosen , Sanjay Krishnaswami , Barthelemy Kuate Defo , Burcu Kucuk Bicer , Ernst J Kuipers (67) , Chanda Kulkarni , Veena S Kulkarni (68) , G Anil Kumar , Hmwe H Kyu , Taavi Lai (69) , Ratilal Lalloo , Tea Lallukka (70) , Hilton Lam (71) , Qing Lan , van C Lansingh , Anders Larsson (72) , Alicia E B Lawrynowicz , Janet L Leasher , James Leigh , Ricky Leung , Carly E Levitz , Bin Li (73, 74) , Yichong Li , Yongmei Li , Stephen S Lim (75) , Maggie Lind (76) , Steven E Lipshultz , Shiwei Liu , Yang Liu (77) , Belinda K Lloyd , Katherine T Lofgren , Giancarlo Logroscino (78) , Katharine J Looker , Joannie Lortet-Tieulent , Paulo A Lotufo , Robyn M Lucas , Raimundas Lunevicius , Ronan A Lyons (79) , Stefan Ma , Michael F Macintyre , Mark T Mackay (80) , Marek Majdan (81) , Reza Malekzadeh , Wagner Marcenes (82) , David J Margolis (83, 84) , Christopher Margono , Melvin B Marzan , Joseph R Masci (85) , Mohammad T Mashal , Richard Matzopoulos , Bongani M Mayosi , Tasara T Mazorodze , Neil W Mcgill (86) , John J Mcgrath , Martin Mckee (87) , Abigail Mclain , Peter A Meaney , Catalina Medina , Man Mohan Mehndiratta , Wubegzier Mekonnen , Yohannes A Melaku , Michele Meltzer , Ziad A Memish (88, 89) , George A Mensah (90) , Atte Meretoja , Francis A Mhimbira , Renata Micha (91, 92) , Ted R Miller , Edward J Mills (93) , Philip B Mitchell , Charles N Mock , Norlinah Mohamed Ibrahim , Karzan A Mohammad (94) , Ali H Mokdad , Glen L D Mola , Lorenzo Monasta , Julio C Montañez Hernandez , Marcella Montico (95) , Thomas J Montine , Meghan D Mooney , Ami R Moore (96) , Maziar Moradi-Lakeh , Andrew E Moran , Rintaro Mori , Joanna Moschandreas , Wilkister N Moturi , Madeline L Moyer , Dariush Mozaffarian (91, 97) , William T Msemburi , Ulrich O Mueller , Mitsuru Mukaigawara , Erin C Mullany , Michele E Murdoch , Joseph Murray (98) , Kinnari S Murthy , Mohsen Naghavi , Aliya Naheed , Kovin S Naidoo (99, 100) , Luigi Naldi (101) , Devina Nand , Vinay Nangia , K M Venkat Narayan , Chakib Nejjari (102) , Sudan P Neupane , Charles R Newton , Marie Ng (103) , Frida N Ngalesoni , Grant Nguyen , Muhammad I Nisar , Sandra Nolte , Ole F Norheim , Rosana E Norman , Bo Norrving (104) , Luke Nyakarahuka , In-Hwan Oh , Takayoshi Ohkubo , Summer L Ohno , Bolajoko O Olusanya , John Nelson Opio , Katrina Ortblad , Alberto Ortiz (105, 106, 107) , Amanda W Pain , Jeyaraj D Pandian , Carlo Irwin A Panelo , Christina Papachristou (108) , Eun-Kee Park , Jae-Hyun Park , Scott B Patten , George C Patton (109) , Vinod K Paul , Boris I Pavlin (110) , Neil Pearce , David M Pereira , Rogelio Perez-Padilla , Fernando Perez-Ruiz , Norberto Perico , Aslam Pervaiz , Konrad Pesudovs , Carrie B Peterson , Max Petzold (111) , Michael R Phillips (112) , Bryan K Phillips (113) , David E Phillips , Frédéric B Piel (114) , Dietrich Plass , Dan Poenaru (115) , Suzanne Polinder , Daniel Pope , Svetlana Popova , Richie G Poulton (116) , Farshad Pourmalek , Dorairaj Prabhakaran (117) , Noela M Prasad (118) , Rachel L Pullan , Dima M Qato , D Alex Quistberg , Anwar Rafay , Kazem Rahimi (119) , Sajjad U Rahman (120) , Murugesan Raju , Saleem M Rana , Homie Razavi , K Srinath Reddy (121) , Amany Refaat , Giuseppe Remuzzi (122) , Serge Resnikoff , Antonio L Ribeiro (123) , Lee Richardson , Jan Hendrik Richardus (124) , D Allen Roberts , David Rojas-Rueda , Luca Ronfani , Gregory A Roth (125) , Dietrich Rothenbacher (126) , David H Rothstein , Jane T Rowley , Nobhojit Roy (127) , George M Ruhago , Mohammad y Saeedi , Sukanta Saha (128) , Mohammad Ali Sahraian , Uchechukwu K A Sampson , Juan R Sanabria , Logan Sandar , Itamar S Santos (129) , Maheswar Satpathy , Monika Sawhney , Peter Scarborough , Ione J Schneider (130) , Ben Schöttker , Austin E Schumacher , David C Schwebel , James G Scott , Soraya Seedat , Sadaf G Sepanlou , Peter T Serina , Edson E Servan-Mori , Katya A Shackelford , Amira Shaheen , Saeid Shahraz , Teresa Shamah Levy , Siyi Shangguan , Jun She , Sara Sheikhbahaei , Peilin Shi (131) , Kenji Shibuya , Yukito Shinohara , Rahman Shiri , Kawkab Shishani , Ivy Shiue , Mark G Shrime , Inga D Sigfusdottir , Donald H Silberberg , Edgar P Simard , Shireen Sindi , Abhishek Singh (132) , Jasvinder A Singh , Lavanya Singh (133, 134) , Vegard Skirbekk , Erica Leigh Slepak , Karen Sliwa (135) , Samir Soneji , Kjetil Søreide , Sergey Soshnikov , Luciano A Sposato , Chandrashekhar T Sreeramareddy , Jeffrey D Stanaway , Vasiliki Stathopoulou , Dan J Stein , Murray B Stein (136) , Caitlyn Steiner , Timothy J Steiner , Antony Stevens , Andrea Stewart (137) , Lars J Stovner , Konstantinos Stroumpoulis , Bruno F Sunguya , Soumya Swaminathan , Mamta Swaroop , Bryan L Sykes , Karen M Tabb , Ken Takahashi (138) , Nikhil Tandon (139) , David Tanne (140) , Marcel Tanner (141) , Mohammad Tavakkoli , Hugh R Taylor (142) , Braden J Te Ao , Fabrizio Tediosi , Awoke M Temesgen , Tara Templin , Margreet ten Have , Eric y Tenkorang , Abdullah S Terkawi , Blake Thomson (143) , Andrew L Thorne-Lyman , Amanda G Thrift , George D Thurston , Taavi Tillmann , Marcello Tonelli (144) , Fotis Topouzis (145) , Hideaki Toyoshima , Jefferson Traebert , Bach X Tran (146) , Matias Trillini , Thomas Truelsen , Miltiadis Tsilimbaris , Emin M Tuzcu , Uche S Uchendu , Kingsley N Ukwaja , Eduardo A Undurraga , Selen B Uzun , Wim H van Brakel , Steven van de Vijver , Coen H van Gool , Jim van Os (147) , Tommi J Vasankari , N Venketasubramanian , Francesco S Violante (148) , Vasiliy V Vlassov (149) , Stein Emil Vollset , Gregory R Wagner , Joseph Wagner (150) , Stephen G Waller (151) , Xia Wan , Haidong Wang , Jianli Wang , Linhong Wang , Tati S Warouw , Scott Weichenthal , Elisabete Weiderpass , Robert G Weintraub , Wang Wenzhi , Andrea Werdecker , Ronny Westerman , Harvey A Whiteford , James D Wilkinson (152) , Thomas N Williams , Charles D Wolfe (153, 154) , Timothy M Wolock , Anthony D Woolf , Sarah Wulf (155) , Brittany Wurtz , Gelin Xu (156, 157) , Lijing L Yan , Yuichiro Yano , Pengpeng Ye , Gökalp K Yentür , Paul Yip (158) , Naohiro Yonemoto , Seok-Jun Yoon (159) , Mustafa Z Younis , Chuanhua Yu (160) , Maysaa E Zaki , Yong Zhao , Yingfeng Zheng , David Zonies , Xiaonong Zou (161) , Joshua A Salomon , Alan D Lopez (162) , Theo Vos
1 STFC - Computational Science and Engineering Department [Daresbury]
2 NET - Neuroépidémiologie Tropicale
3 Service de Chirurgie Thoracique et Vasculaire - Médecine vasculaire [CHU Limoges]
4 Weill Cornell Medical College - Qatar, Qatar Foundation - Education City, Doha
5 APEMAC - Maladies chroniques, santé perçue, et processus d'adaptation
6 Centre d'Investigation Clinique - Epidemiologie Clinique/essais Cliniques Nancy
7 Karolinska Institute
8 CEAZA - Centro de Estudios Avanzados en Zonas Aridas
9 EPFL - Ecole Polytechnique Fédérale de Lausanne
10 Wisconsin Division of Public Health
11 Regional Genetic Service, St Mary's Hospital, Manchester
12 LIM - Laboratoire d'Ingénierie des Matériaux
13 Computer Science Department [Bristol]
14 LBNL - Lawrence Berkeley National Laboratory [Berkeley]
15 SRI-B - Samsung Research &Development Institute India - Bangalore (Groupe Samsung)
16 MRC - Multimedia Research Center
17 Biostat - MINNEAPOLIS - Division of Biostatistics
18 Laboratory of Neurologic Diseases, Mario Negri Institute, Milan
19 University of Southampton
20 Imperial College London
21 Neurology Department
22 Department of Public Health and Primary Care
23 InTRu - Interactions, transferts, ruptures artistiques et culturelles
24 IJM (UMR_7592) - Institut Jacques Monod
25 Institute of Parasitology
26 STAR laboratory
27 VIM (UR 0892) - Unité de recherche Virologie et Immunologie Moléculaires
28 Tennent Institute of Ophthalmology
29 NUS - National University of Singapore
30 Multidisciplinary Nanotechnology Centre
31 Department of Computer Sciences [Scheffield]
32 Cyprus International Institute for the Environment and Public Health
33 Harvard School of Public Health
34 Glasgow Centre for Physical Organic Chemistry
35 King‘s College London
36 UP1 UFR11 - Université Paris 1 Panthéon-Sorbonne - UFR Science Politique
37 NDC - National Diagnostics Centre
38 University of Manchester [Manchester]
39 CEGOT - Porto
40 ALES - Advanced Laboratories on Embedded Systems [Roma]
41 Department of Biology [Miami]
42 Division of Human Nutrition
43 Spatial Ecology and Epidemiology Group
44 Department of Civil Engineering [Hamirpur]
45 GEMMA — Environmental Engineering and Microbiology Research Group, Department of Hydraulic, Maritime and Environmental Engineering
46 INRAP - Institut National de Recherche et d'Analyse Physico-Chimique
47 UCONN - University of Connecticut
48 NILU - Norwegian Institute for Air Research
49 FEMTO-ST - Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174)
50 University of Tehran
51 FAU - Friedrich-Alexander Universität Erlangen-Nürnberg = University of Erlangen-Nuremberg
52 Secretariat of the Pacific Community
53 SAGE - Sociétés, Acteurs, Gouvernement en Europe
54 GW - The George Washington University
55 WSU - Washington State University
56 Phys-ENS - Laboratoire de Physique de l'ENS Lyon
57 IRIT - Institut de recherche en informatique de Toulouse
58 School of Computer Science - China University of Geosciences (China University of Geosciences (East Area))
59 UCL - Université Catholique de Louvain = Catholic University of Louvain
60 DRDO, INMAS - Div Cyclotron & Radiopharmaceut Sci
61 School of Physics and Astronomy [St Andrews]
62 University of Cape Town
63 Department of Neuroscience
64 Department of Computer Science and Engineering [Daejeon] (Chungnam National University)
65 Karolinska Institutet [Stockholm]
66 Lawrence University
67 Gastroenterology & Hepatology
68 TRDDC - Tata Research Development and Design Center
69 MOLTECH-Anjou
70 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
71 Google Inc [Mountain View]
72 FOI - Swedish Defense Research Agency
73 CRIBS - Centre de Recherche en Information Biomédicale sino-français
74 LIST - Laboratory of Image Science and Technology [Nanjing]
75 LGGE - Laboratoire de glaciologie et géophysique de l'environnement
76 School of Business and Informatics
77 CAD Laboratory - Department of Mechanical and Automation Engineering
78 UNIBA - Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro
79 Department of plant pathology and microbiology - centre for sustainable pest and disease management
80 RGU
81 Department of Rheumatology and Connective Tissue Diseases
82 Barts and The London School of Medicine and Dentistry
83 CES - Centre d'économie de la Sorbonne
84 PSE - Paris School of Economics
85 IDSIA - Istituto Dalle Molle di Studi sull'Intelligenza Artificiale
86 Anaesthetics
87 Department of Mathematics
88 College of Medicine
89 Saudi Ministry of Health
90 Institut national des recherches agricoles du Bénin
91 Departments of Epidemiology and Nutrition
92 Unit of Human Nutrition
93 Department of Animal Science
94 University of Virginia
95 Epidemiology and Biostatistics Unit
96 JPL - Jet Propulsion Laboratory
97 Division of Cardiovascular Medicine and Channing Division of Network Medicine
98 Division of Gastroenterology and Hepatology, Department of Immunology
99 Department of Chemistry
100 Scientific Computing Research Unit
101 Department of dermatology
102 Department of epidemiology and Public Health
103 HKBU - Hong Kong Baptist University
104 Skane University Hospital [Lund]
105 SAMOVAR - Services répartis, Architectures, MOdélisation, Validation, Administration des Réseaux
106 TSP - RS2M - Département Réseaux et Services Multimédia Mobiles
107 CNRS - Centre National de la Recherche Scientifique
108 Electrical Engineering and Computer Science Department - Case Western Reserve University
109 University of Melbourne
110 World Health Organization
111 Nordic School of Public Health
112 The James Hutton Institute
113 Sero
114 Evolutionary Ecology of Infectious Disease Group
115 Horia Hulubei National Institute for Physics and Nuclear Engineering
116 Dunedin School of Medicine
117 Department of Physics, Clarendon Laboratory
118 CTIF - Center for TeleInFrastruktur
119 Physikalisches Institut [Freiburg]
120 STL - Savoirs, Textes, Langage (STL) - UMR 8163
121 Dept.of Computer Science
122 Istituto Mario Negri Bergamo
123 UNESP - Universidade Estadual Paulista Júlio de Mesquita Filho = São Paulo State University
124 Department of Public Health
125 UGA UFRM - Université Grenoble Alpes - UFR Médecine
126 Clinical Epidemiology and Aging Research
127 IC UM3 (UMR 8104 / U1016) - Institut Cochin
128 Symantec
129 EMIC - European Microsoft Innovation Center
130 LMPG - Laboratoire de Mécanique, Physique et Géosciences
131 NITD - Novartis Institute for Tropical Diseases
132 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire
133 Departments of Anatomy and Cell Biology
134 Departments of Ophthalmology
135 Departments of Applied Physics [New Haven]
136 CMM - Center for Mathematical Modeling
137 LASP - Laboratory for Atmospheric and Space Physics [Boulder]
138 UEOH - University of Occupational and Environmental Health [Kitakyushu]
139 Department of Computer Science and Engineering [New Delhi]
140 IRPHE - Institut de Recherche sur les Phénomènes Hors Equilibre
141 GlaxoSmithKline
142 Department of Obstetrics, Gynecology and Reproductive Sciences
143 Maclean Building, Benson Lane, Crowmarsh Gifford
144 NEST - Nanoscience Institute
145 Aristotle University of Thessaloniki
146 LICB - Laboratory Of Immune Cell Biology
147 Institute of Human Genetics
148 Occupational Health Unit
149 KTH - KTH Royal Institute of Technology [Stockholm]
150 LMU - Institut für Informatik [München/Munich]
151 NICTA [Eveleigh]
152 Manchester Academic Health Sciences Centre
153 IHPST - Institut d'Histoire et de Philosophie des Sciences et des Techniques
154 UGENT - Universiteit Gent = Ghent University
155 GFZ - German Research Centre for Geosciences - Helmholtz-Centre Potsdam
156 LHEEA - Laboratoire de recherche en Hydrodynamique, Énergétique et Environnement Atmosphérique
157 GeM - Institut de Recherche en Génie Civil et Mécanique
158 Neurorestoration Group
159 CS - Department of Computer Science [KAIST]
160 Heudiasyc - Heuristique et Diagnostic des Systèmes Complexes [Compiègne]
161 Natl Engn Res Ctr Vegetables, Key Lab Biol & Genet Improvement Hort Crops N Chi
162 University Hospital Puerta de Hierro, Madrid
Christopher J L Murray
  • Function : Author
Kyle J Foreman
  • Function : Author
Ayse Abbasoglu Ozgoren
  • Function : Author
Semaw F Abera
  • Function : Author
Jerry P Abraham
  • Function : Author
Ibrahim Abubakar
  • Function : Author
Niveen M Abu-Rmeileh
  • Function : Author
Tom Achoki
  • Function : Author
Ilana N Ackerman
  • Function : Author
Zanfina Ademi
  • Function : Author
Arsène K Adou
  • Function : Author
José C Adsuar
  • Function : Author
Ashkan Afshin
  • Function : Author
Emilie E Agardh
  • Function : Author
Sayed Saidul Alam
  • Function : Author
Deena Alasfoor
  • Function : Author
Mohammed I Albittar
  • Function : Author
Miguel A Alegretti
  • Function : Author
Zewdie A Alemu
  • Function : Author
Rafael Alfonso-Cristancho
  • Function : Author
Samia Alhabib
  • Function : Author
Raghib Ali
  • Function : Author
Mohammad A Almazroa
  • Function : Author
Ubai Alsharif
  • Function : Author
Nelson Alvis-Guzman
  • Function : Author
Azmeraw T Amare
  • Function : Author
Emmanuel A Ameh
  • Function : Author
Walid Ammar
  • Function : Author
Carl Abelardo T Antonio
  • Function : Author
Palwasha Anwari
  • Function : Author
Johan Arnlöv
  • Function : Author
Valentina S Arsic Arsenijevic
  • Function : Author
Al Artaman
  • Function : Author
Rana J Asghar
  • Function : Author
Marco A Avila
  • Function : Author
Baffour Awuah
  • Function : Author
Victoria F Bachman
  • Function : Author
Alaa Badawi
  • Function : Author
Maria C Bahit
  • Function : Author
Suzanne L Barker-Collo
  • Function : Author
Simon Barquera
  • Function : Author
Lars Barregard
  • Function : Author
Lope H Barrero
  • Function : Author
Mohammed O Basulaiman
  • Function : Author
Justin Beardsley
  • Function : Author
Neeraj Bedi
  • Function : Author
Tolesa Bekele
  • Function : Author
Corina Benjet
  • Function : Author
Isabela M Bensenor
  • Function : Author
Habib Benzian
  • Function : Author
Eduardo Bernabé
  • Function : Author
Amelia Bertozzi-Villa
  • Function : Author
Tariku J Beyene
  • Function : Author
Neeraj Bhala
  • Function : Author
Ashish Bhalla
  • Function : Author
Zulfiqar A Bhutta
  • Function : Author
Kelly Bienhoff
  • Function : Author
Boris Bikbov
  • Function : Author
Stan Biryukov
  • Function : Author
Jed D Blore
  • Function : Author
Christopher D Blosser
  • Function : Author
Fiona M Blyth
  • Function : Author
Megan A Bohensky
  • Function : Author
Ian W Bolliger
  • Function : Author
Berrak Bora Başara
  • Function : Author
Dipan Bose
  • Function : Author
Soufiane Boufous
  • Function : Author
Rupert R A Bourne
  • Function : Author
Lindsay N Boyers
  • Function : Author
Michael Brainin
  • Function : Author
Alexandra Brazinova
  • Function : Author
Nicholas J K Breitborde
  • Function : Author
Hermann Brenner
  • Function : Author
Jonathan C Brown
  • Function : Author
Traolach S Brugha
  • Function : Author
Rachelle Buchbinder
  • Function : Author
Geoffrey C Buckle
  • Function : Author
Anne Bulchis
  • Function : Author
Andrew G Bulloch
  • Function : Author
Ismael R Campos-Nonato
  • Function : Author
Hélène Carabin
  • Function : Author
Jonathan R Carapetis
  • Function : Author
Rosario Cárdenas
  • Function : Author
Valeria Caso
  • Function : Author
Carlos A Castañeda-Orjuela
  • Function : Author
Ferrán Catalá-López
  • Function : Author
Fiorella Cavalleri
  • Function : Author
Alanur Çavlin
  • Function : Author
Jung-Chen Chang
  • Function : Author
Fiona J Charlson
  • Function : Author
Honglei Chen
  • Function : Author
Peggy P Chiang
  • Function : Author
Odgerel Chimed-Ochir
  • Function : Author
Massimo Cirillo
Matthew M Coates
  • Function : Author
Luc E Coffeng
  • Function : Author
Megan S Coggeshall
  • Function : Author
Valentina Colistro
  • Function : Author
Samantha M Colquhoun
  • Function : Author
Leslie T Cooper
  • Function : Author
Luis M Coppola
  • Function : Author
Michael H Criqui
  • Function : Author
John A Crump
  • Function : Author
Lucia Cuevas-Nasu
  • Function : Author
Hadi Danawi
  • Function : Author
Lalit Dandona
  • Function : Author
Rakhi Dandona
  • Function : Author
Emily Dansereau
  • Function : Author
Paul I Dargan
  • Function : Author
Adrian Davis
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Dragos V Davitoiu
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Abstract

The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age-sex groups, and countries. The GBD can be used to generate summary measures such as disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) that make possible comparative assessments of broad epidemiological patterns across countries and time. These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development. We used the published GBD 2013 data for age-specific mortality, years of life lost due to premature mortality (YLLs), and years lived with disability (YLDs) to calculate DALYs and HALE for 1990, 1995, 2000, 2005, 2010, and 2013 for 188 countries. We calculated HALE using the Sullivan method; 95% uncertainty intervals (UIs) represent uncertainty in age-specific death rates and YLDs per person for each country, age, sex, and year. We estimated DALYs for 306 causes for each country as the sum of YLLs and YLDs; 95% UIs represent uncertainty in YLL and YLD rates. We quantified patterns of the epidemiological transition with a composite indicator of sociodemographic status, which we constructed from income per person, average years of schooling after age 15 years, and the total fertility rate and mean age of the population. We applied hierarchical regression to DALY rates by cause across countries to decompose variance related to the sociodemographic status variable, country, and time. Worldwide, from 1990 to 2013, life expectancy at birth rose by 6·2 years (95% UI 5·6-6·6), from 65·3 years (65·0-65·6) in 1990 to 71·5 years (71·0-71·9) in 2013, HALE at birth rose by 5·4 years (4·9-5·8), from 56·9 years (54·5-59·1) to 62·3 years (59·7-64·8), total DALYs fell by 3·6% (0·3-7·4), and age-standardised DALY rates per 100 000 people fell by 26·7% (24·6-29·1). For communicable, maternal, neonatal, and nutritional disorders, global DALY numbers, crude rates, and age-standardised rates have all declined between 1990 and 2013, whereas for non-communicable diseases, global DALYs have been increasing, DALY rates have remained nearly constant, and age-standardised DALY rates declined during the same period. From 2005 to 2013, the number of DALYs increased for most specific non-communicable diseases, including cardiovascular diseases and neoplasms, in addition to dengue, food-borne trematodes, and leishmaniasis; DALYs decreased for nearly all other causes. By 2013, the five leading causes of DALYs were ischaemic heart disease, lower respiratory infections, cerebrovascular disease, low back and neck pain, and road injuries. Sociodemographic status explained more than 50% of the variance between countries and over time for diarrhoea, lower respiratory infections, and other common infectious diseases; maternal disorders; neonatal disorders; nutritional deficiencies; other communicable, maternal, neonatal, and nutritional diseases; musculoskeletal disorders; and other non-communicable diseases. However, sociodemographic status explained less than 10% of the variance in DALY rates for cardiovascular diseases; chronic respiratory diseases; cirrhosis; diabetes, urogenital, blood, and endocrine diseases; unintentional injuries; and self-harm and interpersonal violence. Predictably, increased sociodemographic status was associated with a shift in burden from YLLs to YLDs, driven by declines in YLLs and increases in YLDs from musculoskeletal disorders, neurological disorders, and mental and substance use disorders. In most country-specific estimates, the increase in life expectancy was greater than that in HALE. Leading causes of DALYs are highly variable across countries. Global health is improving. Population growth and ageing have driven up numbers of DALYs, but crude rates have remained relatively constant, showing that progress in health does not mean fewer demands on health systems. The notion of an epidemiological transition--in which increasing sociodemographic status brings structured change in disease burden--is useful, but there is tremendous variation in burden of disease that is not associated with sociodemographic status. This further underscores the need for country-specific assessments of DALYs and HALE to appropriately inform health policy decisions and attendant actions. Bill & Melinda Gates Foundation.
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hal-01262808 , version 1 (07-06-2024)

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Christopher J L Murray, Ryan M Barber, Kyle J Foreman, Ayse Abbasoglu Ozgoren, Semaw F Abera, et al.. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition.. The Lancet, 2015, 386 (10009), pp.2145-91. ⟨10.1016/S0140-6736(15)61340-X⟩. ⟨hal-01262808⟩
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