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Journal Articles Epidemiology and Psychiatric Sciences Year : 2021

Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys

Annelieke Roest
Ymkje Anna de Vries
Ali Al-Hamzawi
  • Function : Author
Jordi Alonso
  • Function : Author
Olatunde Ayinde
  • Function : Author
Ronny Bruffaerts
  • Function : Author
Brendan Bunting
  • Function : Author
José Miguel Caldas de Almeida
Giovanni de Girolamo
Louisa Degenhardt
  • Function : Author
Silvia Florescu
  • Function : Author
Oye Gureje
Josep Maria Haro
  • Function : Author
Chiyi Hu
  • Function : Author
Elie Karam
  • Function : Author
Andrzej Kiejna
  • Function : Author
Sing Lee
  • Function : Author
John Mcgrath
Maria Elena Medina-Mora
  • Function : Author
Fernando Navarro-Mateu
  • Function : Author
Daisuke Nishi
  • Function : Author
Marina Piazza
  • Function : Author
José Posada-Villa
  • Function : Author
Kate Scott
Juan Carlos Stagnaro
  • Function : Author
Dan Stein
Yolanda Torres
  • Function : Author
Maria Carmen Viana
  • Function : Author
Zahari Zarkov
  • Function : Author
Ronald Kessler
Peter de Jonge
  • Function : Author

Abstract

Aims - Major depressive disorder (MDD) is characterised by a recurrent course and high comorbidity rates. A lifespan perspective may therefore provide important information regarding health outcomes. The aim of the present study is to examine mental disorders that preceded 12-month MDD diagnosis and the impact of these disorders on depression outcomes. Methods - Data came from 29 cross-sectional community epidemiological surveys of adults in 27 countries ( n = 80 190). The Composite International Diagnostic Interview (CIDI) was used to assess 12-month MDD and lifetime DSM-IV disorders with onset prior to the respondent's age at interview. Disorders were grouped into depressive distress disorders, non-depressive distress disorders, fear disorders and externalising disorders. Depression outcomes included 12-month suicidality, days out of role and impairment in role functioning. Results - Among respondents with 12-month MDD, 94.9% ( s.e. = 0.4) had at least one prior disorder (including previous MDD), and 64.6% ( s.e. = 0.9) had at least one prior, non-MDD disorder. Previous non-depressive distress, fear and externalising disorders, but not depressive distress disorders, predicted higher impairment (OR = 1.4–1.6) and suicidality (OR = 1.5–2.5), after adjustment for sociodemographic variables. Further adjustment for MDD characteristics weakened, but did not eliminate, these associations. Associations were largely driven by current comorbidities, but both remitted and current externalising disorders predicted suicidality among respondents with 12-month MDD. Conclusions - These results illustrate the importance of careful psychiatric history taking regarding current anxiety disorders and lifetime externalising disorders in individuals with MDD.
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Dates and versions

hal-03439267 , version 1 (22-11-2021)

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Annelieke Roest, Ymkje Anna de Vries, Ali Al-Hamzawi, Jordi Alonso, Olatunde Ayinde, et al.. Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys. Epidemiology and Psychiatric Sciences, 2021, 30, ⟨10.1017/S2045796021000573⟩. ⟨hal-03439267⟩

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