Oligodendrocytes CRISPRi Myotonic Dystrophy Oligodendrocyte Transgenic mouse model Glutamate Gene Therapy MBNL PCR Humans Glial cells Endurance training RNA biology Cell penetrating peptide Dynamin 2 DMPK ARN Centronuclear myopathy Dystrophin Knockout Cardiac muscle RNA interference Cell culture model Trinucleotide repeat expansion Heart Motoneuron Trinucleotide Repeat Expansion GABA Antisense oligonucleotide Desmin Myotonic Dystrophy Type 1 Aging Astrocytes Mouse model Myotonic dystrophy mouse models Genotype phenotype correlation CTG repeat contractions CTG repeats Intermediate filament Animals Myotonic Dystrophy type 1 Brain dysfunction CMS Dilated cardiomyopathy Myostatin Exercise Alternative splicing Exercice Quantitative microdialysis Cytoskeleton DMSXL mice Cell model Hypoxia Heart failure Gene editing Autophagy Glucocorticoid-receptor Therapy CONGENITAL MYATHENIC SYNDROME Expression Antisense oligonucleotides DM1 Mice Muscular dystrophy RNA splicing Muscle AAV PacBio BIOLOGIE MOLECULAIRE Male Skeletal muscle Mouse models Transcriptomics Brain In vivo Thérapie génique Myotonic dystrophy Long read sequencing GSK3␤ Acetylcholinesterase knockout mouse Dystrophie myotonique Neuron CTG repeat instability Maximal force Duchenne muscular dystrophy Gene therapy Diaphragm Dystrophie Myotonique Fibrosis Acetylcholinesterase deficiency Central nervous system KNOCKOUT MICE Myelin Acute coronary syndrome CRISPR/Cas9 ACETYLCHOLINESTERASE Myotonic dystrophy type 1 Transgenic mouse Astrocyte Glucocorticoids